| Using Metabolic Profiling Technology to Advance Cell Culture Development
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| By
Michael Milburn
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| Through metabolomics, the metabolic underpinnings of cellular changes can be rapidly pinpointed, directing process development scientists to key areas for cell culture optimization.
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| Managing Cell Line Instability and Its Impact During Cell Line Development
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| By
Robin A. Heller-Harrison
,
Kerstin Crowe
,
Cecilia Cooley
,
Megan Hone
,
Kevin Mccarthy
,
Mark Leonard
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| By considering stability as part of the cell line selection and cell banking paradigm, we can ensure that instability problems are not observed during clinical or commercial manufacturing.
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| The Impact of Cell Culture Medium on Cell Line and Process Development Timelines and Strategies
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| By
Alahari Arunakumari, PhD
,
Xiao-Ping Dai, PhD
,
Joel Goldstein, PhD
,
Claudia Kloth, PhD
,
Haile Ghebremariam
,
Glenn MacIsaac
,
Melissa Wagner
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| ACF medium sped up cell-line development.
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| Production Strategies for Antibody Fragment Therapeutics
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| By
J.M. Liddell, PhD
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| Microbial systems such as E. Coli and yeasts are most effective for producing antibody fragments.
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