Randy Jacinto

Bio-Rad

Apatite-based media have been shown to be effective chromatographic supports for monoclonal antibody (mAb) purification. A two-step purification platform consisting of affinity medium capture followed by a CHT ceramic hydroxyapatite or CFT ceramic fluoroapatite media polishing step results in highly purified chimeric IgG by removing leached protein A, HCP, DNA and MAb aggregates