Bio-Rad

http://www.bio-rad.com/

Antibody-based drugs represent a growing segment of the pharmaceutical industry and one of the most promising classes of therapeutic drugs. However, production of monoclonal antibody (MAb)?based drugs remains very costly, and solutions to lower production costs are needed. The use of ion exchange chromatography to directly capture MAbs from cell culture streams or as a polishing step after an affinity separation may be a way to reduce costs.

Ceramic Hydroxyapatite media requires specific considerations during process-scale chromatography packing. This article describes straightforward best practices for successful and reproducible CHT media column packing at process scale.

Antibody-based drugs represent a growing segment of the pharmaceutical industry and one of the most promising classes of therapeutic drugs.